Is Bisglycinate the Same as Glycinate? Understanding the Difference
The terms "bisglycinate" and "glycinate" are often used in the context of mineral supplements, specifically referring to the form in which the mineral is bound to glycine, an amino acid. While they both involve glycine, there's a key difference that affects absorption and bioavailability. Let's break it down.
Glycinate refers to a mineral chelated with one molecule of glycine. This means one molecule of the mineral is bound to one molecule of glycine. This is a simpler form of chelation.
Bisglycinate, on the other hand, indicates that the mineral is chelated with two molecules of glycine. This means one mineral molecule is bound to two glycine molecules. This double chelation offers potential advantages.
What Does Chelation Mean?
Chelation is a process where a mineral is bound to an amino acid (in this case, glycine). This binding enhances the mineral's absorption and reduces its potential for gastrointestinal upset. Minerals in their ionic or inorganic forms can sometimes irritate the digestive system and are less readily absorbed by the body. Chelation helps to overcome these issues.
How Does Bisglycinate Differ in Absorption?
The additional glycine molecule in bisglycinate might theoretically lead to better absorption and bioavailability compared to glycinate. However, the extent of this difference isn't definitively established across all minerals. More research is needed to fully understand the precise impact of the additional glycine molecule on the bioavailability of various minerals in bisglycinate form.
While bisglycinate may offer advantages, it's crucial to remember that the bioavailability of a mineral also depends on factors like:
- The specific mineral: Different minerals behave differently in the body.
- Individual factors: Age, overall health, and gut health influence absorption.
- Other dietary factors: The presence of other nutrients and substances in the diet can affect mineral absorption.
What are the potential benefits of using bisglycinate?
Although more research is required to establish definitive claims, potential benefits stemming from the enhanced absorption of bisglycinate could include improved mineral utilization by the body, potentially leading to greater effectiveness of the supplement in terms of health benefits it is taken for.
Are there any drawbacks to bisglycinate?
Currently, there are no known significant drawbacks associated with bisglycinate compared to glycinate. However, as with any supplement, individuals with pre-existing medical conditions should consult a healthcare professional before using bisglycinate or glycinate supplements.
Which is better: Bisglycinate or Glycinate?
The "better" form (bisglycinate or glycinate) ultimately depends on the specific mineral and individual factors. While bisglycinate theoretically offers better absorption due to the increased glycine chelation, the difference might be minimal in practice for some minerals. Always check for reputable research and consult a healthcare professional for personalized advice on mineral supplementation.
What about other forms of mineral chelation?
Glycinate and bisglycinate are only two forms of mineral chelation. Other amino acids, such as alanine or lysine, are also used to create chelated minerals. Each has its own characteristics regarding absorption and efficacy.
In summary, while bisglycinate and glycinate are both chelated forms of minerals, bisglycinate involves double chelation with glycine, potentially leading to better absorption. However, further research is needed to fully elucidate the differences in bioavailability for various minerals. Choosing between them often depends on individual needs and preferences. Always prioritize consulting with a healthcare professional for personalized guidance before starting any new supplement regimen.
